Table 3 Estimated cumulative probabilities of live birth and corresponding hazard ratios of failing at ART by discrete smoking patterns (EARTH study, N = 225 couples, 354 ART cycles)
From: Discrete survival model analysis of a couple’s smoking pattern and outcomes of assisted reproduction
| Number of Couples/Cycles | Estimated cumulative probability of live birth, per 100 cyclesa | Adjusted Hazard Ratio (95% CI)b | P-Valueb | |
|---|---|---|---|---|
| Female Smoking History | 0.24 | |||
| Never Smoker | 167/249 | 54.2 (45.8, 64.0) | 1.00 (REF) | |
| Ever Smoker | 58/105 | 45.0 (32.8, 61.8) | 1.30 (0.84, 2.02) | |
| Female Smoking Status | 0.35 | |||
| Never Smoker | 167/249 | 54.1 (45.7, 63.9) | 1.00 (REF) | |
| Former Smoker | 51/93 | 46.9 (34.5, 63.9) | 1.23 (0.79, 1.91) | |
| Current Smoker | 7/12 | 22.7 (5.6, 92.0) | 2.43 (0.64, 9.39) | |
| Male Smoking History | 0.93 | |||
| Never Smoker | 154/235 | 54.0 (46.6, 68.4) | 1.00 (REF) | |
| Ever Smoker | 71/119 | 53.2 (43.1, 65.7) | 1.02 (0.64, 1.63) | |
| Male Smoking Status | 0.75 | |||
| Never Smoker | 154/235 | 54.3 (45.7, 64.6) | 1.00 (REF) | |
| Former Smoker | 55/89 | 56.4 (44.6, 71.5) | 0.94 (0.55, 1.61) | |
| Current Smoker | 16/30 | 46.7 (30.6, 72.7) | 1.25 (0.69, 2.25) | |
| Couples Ever Smoking Status | 0.59 | |||
| Female and Male Never Smokers | 121/172 | 54.7 (45.7, 65.4) | 1.00 (REF) | |
| Female Never Smoker, Male Ever Smoker | 46/77 | 50.7 (38.4, 67.0) | 1.12 (0.69, 1.84) | |
| Female Ever Smoker, Male Never Smoker | 33/63 | 42.2 (28.7, 62.0) | 1.43 (0.85, 2.41) | |
| Female and Male Ever Smokers | 25/42 | 47.5 (31.8, 70.8) | 1.24 (0.62, 2.46) |